1-Methylpiperazine → 2-(4-chlorocinnamyl)-6-(3-fluoro-4-methoxyphenyl)-4-(4-methyl-1-piperazinyl)methyl-2H-pyridazin-3-one

Reaction equation

C(O[C:6]([N:8]1[CH2:13][CH2:12][N:11](C2C(=O)N(CC(C)C)N=C(C3C=CC(C)=C(F)C=3)C=2C)[CH2:10][CH2:9]1)=O)(C)(C)C.[Cl:34][C:35]1[CH:65]=[CH:64][C:38]([CH:39]=[CH:40][CH2:41][N:42]2[C:47](=[O:48])[C:46]([CH2:49]OS(C)(=O)=O)=[CH:45][C:44]([C:55]3[CH:60]=[CH:59][C:58]([O:61][CH3:62])=[C:57]([F:63])[CH:56]=3)=[N:43]2)=[CH:37][CH:36]=1.CN1CCNCC1>>[Cl:34][C:35]1[CH:36]=[CH:37][C:38]([CH:39]=[CH:40][CH2:41][N:42]2[C:47](=[O:48])[C:46]([CH2:49][N:11]3[CH2:12][CH2:13][N:8]([CH3:6])[CH2:9][CH2:10]3)=[CH:45][C:44]([C:55]3[CH:60]=[CH:59][C:58]([O:61][CH3:62])=[C:57]([F:63])[CH:56]=3)=[N:43]2)=[CH:64][CH:65]=1