Tetrahydrofuran → 6-(4-Hydroxy-cyclohexyl)-1-methyl-1H-indole-3-carboxylic acid methyl ester

Reaction equation

[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][n:7]([CH3:21])[c:8]2[cH:9][c:10]([C:14]3=[CH:15][CH2:16][CH:17]([OH:20])[CH2:18][CH2:19]3)[cH:11][cH:12][c:13]12.[H:22][H:23].[O:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1.[Pd:29]>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][n:7]([CH3:21])[c:8]2[cH:9][c:10]([CH:14]3[CH2:15][CH2:16][CH:17]([OH:20])[CH2:18][CH2:19]3)[cH:11][cH:12][c:13]12