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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80574Generated: October 26, 2026

4-Chloro-2-nitrobenzoic acid → Tert-butyl 2-(benzyloxy)-4-chlorobenzoate

https://huagongshe.com/reaction/80574

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-2-nitrobenzoic acidHCID 80475—
Reactant2-(Benzyloxy)-4-chlorobenzoic acidHCID 22452154—
ProductTert-butyl 2-(benzyloxy)-4-chlorobenzoateHCID 70815245—

Reaction Steps

Instead of the starting material, that is, 4-chloro-2-nitrobenzoic acid, of Reference Example 6, 2-(benzyloxy)-4-chlorobenzoic acid was used for a similar procedure as in Reference Example 6 to obtain tert-butyl 2-(benzyloxy)-4-chlorobenzoate (compound S12a).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846660B2
Source datasetuspto-grants-2014_09
ORD IDord-c70a28985e2b45fcb6c4a427607c4667
Source noteuspto-grants-2014_09