Hydrochloric Acid → 3-Chloro-5-(trifluoromethyl)pyridin-2-ol

HRID 805950

Reaction equation

[CH3:15][S:16]([CH3:17])=[O:18].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[cH:6][c:7]1[Cl:8].[ClH:19].[Na+:14].[OH-:13].[OH2:20]>>[c:2]1(=[O:18])[nH:3][cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[cH:6][c:7]1[Cl:8]

Participants

Reactant 6

HCID 313Hydrochloric Acid

HCID 679Dimethyl Sulfoxide

HCID 923Sodium ion

HCID 961Hydroxide

HCID 962Water

HCID 1122342,3-Dichloro-5-(trifluoromethyl)pyridine

Product 1

HCID 7254363-Chloro-5-(trifluoromethyl)pyridin-2-ol

Sources & evidence

ORD record: ord-a22212a60a1a47f990858996bfbcdbef
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Linked notes

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