Acetone → 2-(3-Bromo-5-fluoropyridin-4-yl)propan-2-ol
Reaction equation
[Br:13][c:14]1[cH:15][n:16][cH:17][c:18]([F:20])[cH:19]1.[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[CH3:21][C:22]([CH3:23])=[O:24].[CH:6]([NH:7][CH:8]([CH3:9])[CH3:10])([CH3:11])[CH3:12]>>[Br:13][c:14]1[cH:15][n:16][cH:17][c:18]([F:20])[c:19]1[C:22]([CH3:21])([CH3:23])[OH:24]Participants
6
Sources & evidence
- ORD record
- ord-81eceeca3e8d4bc19218d621590ea5db
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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