Toluene → 4-Hydroxymethyl-2-meth yl-8-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-5,8-dihydro-6H-pyrido[2,3-d]pyrimidin-7-one

Reaction equation

[CH3:37][S:38](=[O:39])(=[O:40])[OH:41].[CH3:42][c:43]1[cH:44][cH:45][cH:46][cH:47][cH:48]1.[OH:1][CH2:2][c:3]1[c:4]2[c:5]([n:6][c:7]([CH3:9])[n:8]1)[N:10]([CH2:15][c:16]1[cH:17][cH:18][c:19](-[c:22]3[c:23](-[c:28]4[n:29][n:30][n:31][n:32]4[C:33]([CH3:34])([CH3:35])[CH3:36])[cH:24][cH:25][cH:26][cH:27]3)[cH:20][cH:21]1)[C:11](=[O:14])[CH2:12][CH2:13]2>>[OH:1][CH2:2][c:3]1[c:4]2[c:5]([n:6][c:7]([CH3:9])[n:8]1)[N:10]([CH2:15][c:16]1[cH:17][cH:18][c:19](-[c:22]3[c:23](-[c:28]4[n:29][n:30][n:31][nH:32]4)[cH:24][cH:25][cH:26][cH:27]3)[cH:20][cH:21]1)[C:11](=[O:14])[CH2:12][CH2:13]2