Methylamine → N-Methyl-5-(4-{[1-(1-methylethyl)-4-piperidinyl]methyl}-1-piperidinyl)-2-pyridinecarboxamide

Reaction equation

[CH3:1][CH:2]([CH3:3])[N:4]1[CH2:5][CH2:6][CH:7]([CH2:10][CH:11]2[CH2:12][CH2:13][N:14]([c:17]3[cH:18][cH:19][c:20]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[n:21][cH:22]3)[CH2:15][CH2:16]2)[CH2:8][CH2:9]1.[CH3:30][NH2:31]>>[CH3:1][CH:2]([CH3:3])[N:4]1[CH2:5][CH2:6][CH:7]([CH2:10][CH:11]2[CH2:12][CH2:13][N:14]([c:17]3[cH:18][cH:19][c:20]([C:23](=[O:24])[NH:31][CH3:30])[n:21][cH:22]3)[CH2:15][CH2:16]2)[CH2:8][CH2:9]1

Participants

Reactant 2

HCID 6329Methylamine

HCID 116898931,1-Dimethylethyl 5-(4-{[1-(1-methylethyl)-4-piperidinyl]methyl}-1-piperidinyl)-2-pyridinecarboxylate

Product 1

HCID 11494207N-Methyl-5-(4-{[1-(1-methylethyl)-4-piperidinyl]methyl}-1-piperidinyl)-2-pyridinecarboxamide

Sources & evidence

ORD record: ord-cafe3d00659240fe9b40d16eb7c5762e
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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