Dimethylacetamide → 1'-(5-(3-methoxyphenyl)-1H-benzimidazol-2-yl)-spiro[isobenzofuran-1,4'-piperidin]-3-one

HRID 808827

Reaction equation

[CH3:34][C:35]([N:36]([CH3:37])[CH3:38])=[O:39].[Cl:1][c:2]1[nH:3][c:4]2[c:5]([n:6]1)[cH:7][cH:8][c:9](-[c:11]1[cH:12][c:13]([O:17][CH3:18])[cH:14][cH:15][cH:16]1)[cH:10]2.[NH:19]1[CH2:20][CH2:21][C:22]2([O:23][C:24](=[O:31])[c:25]3[cH:26][cH:27][cH:28][cH:29][c:30]32)[CH2:32][CH2:33]1>>[c:2]1([N:19]2[CH2:20][CH2:21][C:22]3([O:23][C:24](=[O:31])[c:25]4[cH:26][cH:27][cH:28][cH:29][c:30]43)[CH2:32][CH2:33]2)[n:3][c:4]2[c:5]([nH:6]1)[cH:7][cH:8][c:9](-[c:11]1[cH:12][c:13]([O:17][CH3:18])[cH:14][cH:15][cH:16]1)[cH:10]2

Participants

Reactant 3

HCID 31374Dimethylacetamide

HCID 98342553H-spiro(isobenzofuran-1,4'-piperidin)-3-one

HCID 120716652-Chloro-5-(3-methoxyphenyl)benzimidazole

Product 1

HCID 1784896661'-(5-(3-methoxyphenyl)-1H-benzimidazol-2-yl)-spiro[isobenzofuran-1,4'-piperidin]-3-one

Sources & evidence

ORD record: ord-8023d1e0177a438f9c84b0b4030c9803
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Linked notes

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