Acetic Acid → 1-Tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one

HRID 809816

Reaction equation

HRID 809816 reaction equation
[CH3:28][C:29](=[O:30])[OH:31].[CH3:33][CH2:34][OH:35].[ClH:32].[OH:1][C:2]1=[C:8]([C:9]([O:10][CH2:11][CH3:12])=[O:13])[CH2:7][CH2:6][N:5]([S:14](=[O:15])(=[O:16])[c:17]2[cH:18][cH:19][c:20]([CH3:21])[cH:22][cH:23]2)[c:4]2[c:3]1[cH:27][cH:26][cH:25][cH:24]2.[S:36](=[O:37])(=[O:38])([OH:39])[OH:40]>>[O:1]=[C:2]1[c:3]2[c:4]([cH:24][cH:25][cH:26][cH:27]2)[N:5]([S:14](=[O:15])(=[O:16])[c:17]2[cH:18][cH:19][c:20]([CH3:21])[cH:22][cH:23]2)[CH2:6][CH2:7][CH2:8]1

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 702EthanolHCID 1118Sulfuric AcidHCID 54718720ethyl 5-hydroxy-1-tosyl-2,3-dihydro-1H-benzo[b]azepine-4-carboxylate

Product 1

HCID 2668521-Tosyl-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one

Sources & evidence

ORD record
ord-5d73da89c4d04a5396422679201f53f1
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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