Hydrochloric Acid → (4-Methanesulfonyl-biphenyl-2-yl)-(2-trifluoromethyl-7,8-dihydro-5H-[1,6]naphthyridin-6-yl)-methanone

HRID 810385

Reaction equation

HRID 810385 reaction equation
[CH3:16][S:17](=[O:18])(=[O:19])[c:20]1[cH:21][c:22]([C:32](=[O:33])[OH:34])[c:23](-[c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[cH:24][cH:25]1.[ClH:1].[F:2][C:3]([c:4]1[n:5][c:6]2[c:11]([cH:12][cH:13]1)[CH2:10][NH:9][CH2:8][CH2:7]2)([F:14])[F:15]>>[F:2][C:3]([c:4]1[n:5][c:6]2[c:11]([cH:12][cH:13]1)[CH2:10][N:9]([C:32]([c:22]1[cH:21][c:20]([S:17]([CH3:16])(=[O:18])=[O:19])[cH:25][cH:24][c:23]1-[c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)=[O:33])[CH2:8][CH2:7]2)([F:14])[F:15]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 534719842-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridineHCID 574452544-(methylsulfonyl)-Biphenyl-2-carboxylic acid

Product 1

HCID 11576214(4-Methanesulfonyl-biphenyl-2-yl)-(2-trifluoromethyl-7,8-dihydro-5H-[1,6]naphthyridin-6-yl)-methanone

Sources & evidence

ORD record
ord-079895d0ece64c42bb8d9532ad39930f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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