Toluene → 6-(4-Methyl-piperazin-1-yl)-4-o-tolyl-nicotinonitrile
Reaction equation
[CH3:17][N:18]1[CH2:19][CH2:20][NH:21][CH2:22][CH2:23]1.[CH3:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6]#[N:7])[c:8](-[c:10]2[c:11]([CH3:16])[cH:12][cH:13][cH:14][cH:15]2)[cH:9]1>>[c:2]1([N:21]2[CH2:20][CH2:19][N:18]([CH3:17])[CH2:23][CH2:22]2)[n:3][cH:4][c:5]([C:6]#[N:7])[c:8](-[c:10]2[c:11]([CH3:16])[cH:12][cH:13][cH:14][cH:15]2)[cH:9]1Participants
4
Sources & evidence
- ORD record
- ord-23319892c7ee44b5bcf39358d91adfd6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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