Hydrochloric Acid → HCID 55285125, compound

Reaction equation

C(OC(=O)[NH:7][C@@H:8]1[CH2:13][CH2:12][N:11]([CH3:14])[CH2:10][C@H:9]1[O:15][CH3:16])(C)(C)C.Cl>>[CH3:16][O:15][C@H:9]1[C@H:8]([NH2:7])[CH2:13][CH2:12][N:11]([CH3:14])[CH2:10]1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 58522509HCID 58522509, compound

Product 1

HCID 55285125HCID 55285125, compound

Procedure

Tert-butyl((3R,4R)-3-methoxy-1-methyl-piperidin-4-yl)-carbamate (3.01 g) is combined with HCl (4 molar in dioxane, 25 mL). After 1 h the reaction mixture is freed from the solvent in vacuo and used in the next step without any further purification.

Workup

customused in the next step without any further purification

Sources & evidence

ORD record: ord-b1c6daa410044df38f2e64041c452c3a
Source dataset: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08846689B2

Reaction notes

Loading…