Phosphorus oxychloride → 4,8-Dichloro-7-methoxy-2-[4-(propan-2-yl)-1,3-thiazol-2-yl]quinoline
Reaction equation
[Cl:1][c:2]1[c:3]([O:21][CH3:22])[cH:4][cH:5][c:6]2[c:7]([OH:20])[cH:8][c:9](-[c:12]3[s:13][cH:14][c:15]([CH:17]([CH3:18])[CH3:19])[n:16]3)[n:10][c:11]12.[P:23]([Cl:24])([Cl:25])([Cl:26])=[O:27]>>[Cl:1][c:2]1[c:3]([O:21][CH3:22])[cH:4][cH:5][c:6]2[c:7]([Cl:25])[cH:8][c:9](-[c:12]3[s:13][cH:14][c:15]([CH:17]([CH3:18])[CH3:19])[n:16]3)[n:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-f2131269f9324a189bfda6da76d73050
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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