Water → 4-Chloro-6-(4-fluorophenyl)-2-methylpyrimidine

HRID 816466

Reaction equation

HRID 816466 reaction equation
[CH3:22][C:23]#[N:24].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([CH3:15])[n:11][c:12]([OH:14])[cH:13]2)[cH:6][cH:7]1.[OH2:21].[P:16]([Cl:17])([Cl:18])([Cl:19])=[O:20]>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([CH3:15])[n:11][c:12]([Cl:18])[cH:13]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 962WaterHCID 6342AcetonitrileHCID 24813Phosphorus oxychlorideHCID 178418772HCID 178418772, compound

Product 1

HCID 158701424-Chloro-6-(4-fluorophenyl)-2-methylpyrimidine

Sources & evidence

ORD record
ord-ab4800056e1d46ee91faf1c905a164d4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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