Chloride → 2,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine

HRID 816598

Reaction equation

HRID 816598 reaction equation
[Al+3:20].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[cH:9][cH:10][c:11]2[n:12][c:13]([Cl:18])[n:14][c:15]([Cl:17])[c:16]12.[Cl-:19].[Cl-:21].[Cl-:22].[Cl:23][CH:24]([Cl:25])[Cl:26].[Cl:27][c:28]1[c:29]([Cl:30])[cH:31][cH:32][cH:33][cH:34]1>>[nH:8]1[cH:9][cH:10][c:11]2[n:12][c:13]([Cl:18])[n:14][c:15]([Cl:17])[c:16]12

Participants

6

Reactant 5

HCID 312Chloride3×HCID 6212ChloroformHCID 72391,2-DichlorobenzeneHCID 104727Aluminum CationHCID 147277655-benzyl-2,4-dichloro-5H-pyrrolo[3,2-d]pyrimidine

Product 1

HCID 53750532,4-Dichloro-5H-pyrrolo[3,2-d]pyrimidine

Sources & evidence

ORD record
ord-e46122dad60546c98c112cafcc5ccee4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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