Potassium Cation → Dimethyl 1-benzylpiperidine-3,5-dicarboxylate

HRID 816716

Reaction equation

HRID 816716 reaction equation
[CH2:21]([c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)[Br:28].[CH3:29][C:30]#[N:31].[K+:15].[K+:16].[NH:1]1[CH2:2][CH:3]([C:11](=[O:12])[O:13][CH3:14])[CH2:4][CH:5]([C:7](=[O:8])[O:9][CH3:10])[CH2:6]1.[O-:17][C:18]([O-:19])=[O:20]>>[N:1]1([CH2:21][c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[CH2:2][CH:3]([C:11](=[O:12])[O:13][CH3:14])[CH2:4][CH:5]([C:7](=[O:8])[O:9][CH3:10])[CH2:6]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 7498Benzyl BromideHCID 19660Carbonate IonHCID 49761012Dimethyl piperidine-3,5-dicarboxylate

Product 1

HCID 57905194Dimethyl 1-benzylpiperidine-3,5-dicarboxylate

Sources & evidence

ORD record
ord-4cf014869b5f426588bd814e858fd254
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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