Ethyl Bromide → Diethyl ((1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl)phosphonate

Reaction equation

[Br:1][CH2:2][N:3]1[C:4](=[O:13])[c:5]2[c:6]([cH:9][cH:10][cH:11][cH:12]2)[C:7]1=[O:8].[CH2:24]([Br:25])[CH3:26].[P:14]([O:15][CH2:16][CH3:17])([O:18][CH2:19][CH3:20])[O:21][CH2:22][CH3:23]>>[CH2:2]([N:3]1[C:4](=[O:13])[c:5]2[c:6]([cH:9][cH:10][cH:11][cH:12]2)[C:7]1=[O:8])[P:14]([O:15][CH2:16][CH3:17])([O:18][CH2:19][CH3:20])=[O:21]

Participants

Reactant 3

HCID 6332Ethyl Bromide

HCID 31215Triethyl phosphite

HCID 792441H-Isoindole-1,3(2H)-dione, 2-(bromomethyl)-

Product 1

HCID 1924456Diethyl ((1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)methyl)phosphonate

Sources & evidence

ORD record: ord-338b555bce554fbaa9aa51fdd12d60f7
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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