Methanol → 2-((4-(Aminomethyl)benzyl)oxy)pyrimidin-4-amine

HRID 821492

Reaction equation

HRID 821492 reaction equation
[CH3:24][NH2:25].[CH3:26][OH:27].[NH2:1][c:2]1[n:3][c:4]([O:8][CH2:9][c:10]2[cH:11][cH:12][c:13]([CH2:14][NH:15][C:16](=[O:17])[C:18]([F:19])([F:20])[F:21])[cH:22][cH:23]2)[n:5][cH:6][cH:7]1>>[NH2:1][c:2]1[n:3][c:4]([O:8][CH2:9][c:10]2[cH:11][cH:12][c:13]([CH2:14][NH2:15])[cH:22][cH:23]2)[n:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 887MethanolHCID 6329MethylamineHCID 86657016N-(4-((4-Aminopyrimidin-2-yloxy)methyl)benzyl)-2,2,2-trifluoroacetamide

Product 1

HCID 584459102-((4-(Aminomethyl)benzyl)oxy)pyrimidin-4-amine

Sources & evidence

ORD record
ord-8c719e1e3c874f818a4375889c050fc3
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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