Tetrahydrofuran → 4-Amino-N-(1-azabicyclo[3.2.1]oct-5-ylmethyl)-5-chloro-2-methoxybenzamide

HRID 823255

Reaction equation

HRID 823255 reaction equation
[N:14]12[CH2:15][CH2:16][CH2:17][C:18]([CH2:22][NH2:23])([CH2:19][CH2:20]1)[CH2:21]2.[NH2:1][c:2]1[cH:3][c:4]([O:12][CH3:13])[c:5]([C:6](=[O:7])[OH:8])[cH:9][c:10]1[Cl:11].[O:24]1[CH2:25][CH2:26][CH2:27][CH2:28]1>>[NH2:1][c:2]1[cH:3][c:4]([O:12][CH3:13])[c:5]([C:6](=[O:8])[NH:23][CH2:22][C:18]23[CH2:17][CH2:16][CH2:15][N:14]([CH2:20][CH2:19]2)[CH2:21]3)[cH:9][c:10]1[Cl:11]

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 816264-Amino-5-chloro-2-methoxybenzoic acidHCID 19795979{1-Azabicyclo[3.2.1]octan-5-yl}methanamine

Product 1

HCID 197959744-Amino-N-(1-azabicyclo[3.2.1]oct-5-ylmethyl)-5-chloro-2-methoxybenzamide

Sources & evidence

ORD record
ord-47601bb73a2f49c395424fbdb1925add
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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