Diisopropylethylamine → 4-Chloro-2-[(3-hydroxy-1-phenylpropyl)amino]benzonitrile
Reaction equation
[CH:22]([N:23]([CH:24]([CH3:25])[CH3:26])[CH2:27][CH3:28])([CH3:29])[CH3:30].[Cl:12][c:13]1[cH:14][c:15]([F:21])[c:16]([C:17]#[N:18])[cH:19][cH:20]1.[NH2:1][CH:2]([CH2:3][CH2:4][OH:5])[c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1>>[NH:1]([CH:2]([CH2:3][CH2:4][OH:5])[c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1)[c:15]1[cH:14][c:13]([Cl:12])[cH:20][cH:19][c:16]1[C:17]#[N:18]Participants
4
Sources & evidence
- ORD record
- ord-e89c7b5b71c9433f86ecdd2c3182e73b
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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