Tetramethylammonium → Tert-butyl 3-(5-chloro-2-hydroxyphenyl)azetidine-1-carboxylate

HRID 824251Notes

Reaction equation

HRID 824251 reaction equation
[C:1]([Si:2]([CH3:3])([CH3:4])[O:6][c:7]1[c:8]([CH:14]2[CH2:15][N:16]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:17]2)[cH:9][c:10]([Cl:13])[cH:11][cH:12]1)([CH3:5])([CH3:25])[CH3:26].[CH3:28][N+:29]([CH3:30])([CH3:31])[CH3:32].[F-:27].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1>>[OH:6][c:7]1[c:8]([CH:14]2[CH2:15][N:16]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:17]2)[cH:9][c:10]([Cl:13])[cH:11][cH:12]1

Participants

5

Reactant 4

HCID 6380TetramethylammoniumHCID 8028TetrahydrofuranHCID 28179Fluoride IonHCID 59436503tert-Butyl3-(2-{[tert-butyl(dimethyl)silyl]oxy)-5-chlorophenyl)azetidine-1-carboxylate

Product 1

HCID 59436608Tert-butyl 3-(5-chloro-2-hydroxyphenyl)azetidine-1-carboxylate

Sources & evidence

ORD record
ord-17de38203c6d4a93a23db25e57119839
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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