Methane → 4-(2-Hydroxyphenyl)-2,2-dimethyl-5-oxopiperazine-1-carboxylic acid t-butyl ester

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[C:9]([CH3:29])([CH3:30])[CH2:10][N:11]([c:15]2[c:16]([O:21][CH2:22][c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[cH:17][cH:18][cH:19][cH:20]2)[C:12](=[O:14])[CH2:13]1.[C:35].[CH3:33][OH:34].[H:31][H:32].[Pd:36]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[C:9]([CH3:29])([CH3:30])[CH2:10][N:11]([c:15]2[c:16]([OH:21])[cH:17][cH:18][cH:19][cH:20]2)[C:12](=[O:14])[CH2:13]1