Acetonitrile → 7-Methoxy-1-methyl-3,4-dihydroisoquinoline

HRID 824883

Reaction equation

[CH3:20][C:21]#[N:22].[CH3:6][O:7][c:8]1[cH:9][cH:10][c:11]([CH2:14][CH2:15][NH:16][C:17]([CH3:18])=[O:19])[cH:12][cH:13]1.[P:1]([Cl:2])([Cl:3])([Cl:4])=[O:5]>>[CH3:6][O:7][c:8]1[cH:9][cH:10][c:11]2[c:12]([cH:13]1)[C:17]([CH3:18])=[N:16][CH2:15][CH2:14]2

Participants

Reactant 3

HCID 6342Acetonitrile

HCID 24813Phosphorus oxychloride

HCID 584258N-(2-(4-Methoxyphenyl)ethyl)acetamide

Product 1

HCID 150619777-Methoxy-1-methyl-3,4-dihydroisoquinoline

Sources & evidence

ORD record: ord-123edc0f26cd4096aabb63efba92cebc
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Linked notes

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