Hydrochloric Acid → 2-Chloro-N-[3-chloro-4-(trifluoromethyl)benzyl]-4-[(1,2,4-thiadiazol-5-ylamino)sulfonyl]benzamide

Reaction equation

[Cl:1][c:2]1[cH:3][c:4]([S:23](=[O:24])(=[O:25])[Cl:26])[cH:5][cH:6][c:7]1[C:8](=[O:9])[NH:10][CH2:11][c:12]1[cH:13][c:14]([Cl:22])[c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]1.[ClH:33].[NH2:27][c:28]1[n:29][cH:30][n:31][s:32]1>>[Cl:1][c:2]1[cH:3][c:4]([S:23](=[O:24])(=[O:25])[NH:27][c:28]2[n:29][cH:30][n:31][s:32]2)[cH:5][cH:6][c:7]1[C:8](=[O:9])[NH:10][CH2:11][c:12]1[cH:13][c:14]([Cl:22])[c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]1

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 2902745-Amino-1,2,4-thiadiazole

HCID 577321163-Chloro-4-({[3-chloro-4-(trifluoromethyl)benzyl]amino}carbonyl)benzenesulfonyl chloride

Product 1

HCID 577321642-Chloro-N-[3-chloro-4-(trifluoromethyl)benzyl]-4-[(1,2,4-thiadiazol-5-ylamino)sulfonyl]benzamide

Sources & evidence

ORD record: ord-3b8dec4514e5468eb0052f48463f71d4
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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