Dimethylformamide → 3-(2-Fluoro-4-nitrophenoxy)-2,6-dimethyl-pyridine

HRID 825609

Reaction equation

HRID 825609 reaction equation
[C:10](=[O:11])([O-:12])[O-:13].[CH3:1][c:2]1[n:3][c:4]([CH3:9])[cH:5][cH:6][c:7]1[OH:8].[Cs+:14].[Cs+:15].[F:16][c:17]1[cH:18][c:19]([N+:24](=[O:25])[O-:26])[cH:20][cH:21][c:22]1[F:23].[O:27]=[CH:28][N:29]([CH3:30])[CH3:31]>>[CH3:1][c:2]1[n:3][c:4]([CH3:9])[cH:5][cH:6][c:7]1[O:8][c:22]1[c:17]([F:16])[cH:18][c:19]([N+:24](=[O:25])[O-:26])[cH:20][cH:21]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 707322,6-Dimethyl-3-pyridinolHCID 104967Cesium cation2×HCID 1230531,2-Difluoro-4-nitrobenzene

Product 1

HCID 592873193-(2-Fluoro-4-nitrophenoxy)-2,6-dimethyl-pyridine

Sources & evidence

ORD record
ord-96abfe2f596c4a40ad90d0454d50e6b9
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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