Water → N-((3-bromophenyl)methyl)-N-(1-(tert-butyloxycarbonyl)piperidin-4-yl)-4-methoxyphenylacetamide

HRID 826877

Reaction equation

HRID 826877 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH2:8][NH:9][CH:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[cH:5][cH:6][cH:7]1.[CH3:32][O:33][c:34]1[cH:35][cH:36][c:37]([CH2:40][C:41](=[O:42])[Cl:43])[cH:38][cH:39]1.[CH:23]([N:24]([CH:25]([CH3:26])[CH3:27])[CH2:28][CH3:29])([CH3:30])[CH3:31].[Cl:45][CH2:46][Cl:47].[OH2:44]>>[Br:1][c:2]1[cH:3][c:4]([CH2:8][N:9]([CH:10]2[CH2:11][CH2:12][N:13]([C:16](=[O:17])[O:18][C:19]([CH3:20])([CH3:21])[CH3:22])[CH2:14][CH2:15]2)[C:41]([CH2:40][c:37]2[cH:36][cH:35][c:34]([O:33][CH3:32])[cH:39][cH:38]2)=[O:42])[cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 962WaterHCID 6344DichloromethaneHCID 81531DiisopropylethylamineHCID 27346884-Methoxyphenylacetyl chlorideHCID 11617611tert-Butyl 4-(3-bromobenzylamino)piperidine-1-carboxylate

Product 1

HCID 22643473N-((3-bromophenyl)methyl)-N-(1-(tert-butyloxycarbonyl)piperidin-4-yl)-4-methoxyphenylacetamide

Sources & evidence

ORD record
ord-d67b32ec769c4d44ab6d9dc175dbe44b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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