Ethylene Glycol → 4,6-Diamino-2-(2-hydroxy-ethoxy)-nicotinonitrile

HRID 826926Notes

Reaction equation

[Br:6][c:7]1[c:8]([C:9]#[N:10])[c:11]([NH2:16])[cH:12][c:13]([NH2:15])[n:14]1.[Na:5].[OH2:17].[OH:1][CH2:2][CH2:3][OH:4]>>[O:1]([CH2:2][CH2:3][OH:4])[c:7]1[c:8]([C:9]#[N:10])[c:11]([NH2:16])[cH:12][c:13]([NH2:15])[n:14]1

Participants

Reactant 4

HCID 174Ethylene Glycol

HCID 962Water

HCID 1706684,6-Diamino-2-bromo-3-pyridinecarbonitrile

HCID 5360545Sodium

Product 1

HCID 669208504,6-Diamino-2-(2-hydroxy-ethoxy)-nicotinonitrile

Sources & evidence

ORD record: ord-95eb3e3cebd44d92b195a7e9308dc7e3
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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