Dichloromethane → 1-[2-(2-Fluorophenoxy)ethyl]piperazine

HRID 827328

Reaction equation

HRID 827328 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][O:16][c:17]2[c:18]([F:23])[cH:19][cH:20][cH:21][cH:22]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:31][CH2:32][Cl:33].[OH:24][C:25]([C:26]([F:27])([F:28])[F:29])=[O:30]>>[NH:8]1[CH2:9][CH2:10][N:11]([CH2:14][CH2:15][O:16][c:17]2[c:18]([F:23])[cH:19][cH:20][cH:21][cH:22]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 672988034-[2-(2-Fluorophenoxy)ethyl]piperazine-1-carboxylic acid tert-butyl ester

Product 1

HCID 7627031-[2-(2-Fluorophenoxy)ethyl]piperazine

Sources & evidence

ORD record
ord-f80471e55833444c872afc909b549b46
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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