N#N.[Si:3]([O:10][CH2:11][C:12]1[N:13]=[C:14]([CH:17]([OH:19])[CH3:18])[O:15][CH:16]=1)([C:6]([CH3:9])([CH3:8])[CH3:7])([CH3:5])[CH3:4]>C(C#N)(C)=O.O=[Mn]=O>[Si:3]([O:10][CH2:11][C:12]1[N:13]=[C:14]([C:17](=[O:19])[CH3:18])[O:15][CH:16]=1)([C:6]([CH3:9])([CH3:7])[CH3:8])([CH3:5])[CH3:4]In a flame dried round-bottomed flask equipped with a magnetic stir bar and under inert atmosphere (N2), a solution of 1-(4-(((tert-butyldimethylsilyl)oxy)methyl)oxazol-2-yl)ethanol (260 mg, 1.01 mmol) in AcCN (7.1 mL) was treated at rt with MnO2 (1488 mg, 5.05 mmol) and the resulting mixture was stirred overnight at rt. The reaction mixture was filtered and the solvent was removed under reduced pressure to give the title compound as a yellow oil. TLC: rf (2:1 hept-EA)=0.55. LC-MS-conditions 07: tR=0.96 min, [M]+=255.89.
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