Dichloromethane → Cyclopentyl 2-amino-2-cyclohexylacetate

Reaction equation

[CH:1]1([O:6][C:7]([CH:8]([CH:9]2[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]2)[NH:15][C:16]([O:17][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:22])=[O:23])[CH2:2][CH2:3][CH2:4][CH2:5]1.[Cl:31][CH2:32][Cl:33].[Cl:34][CH2:35][Cl:36].[F:24][C:25]([F:26])([F:27])[C:28]([OH:29])=[O:30]>>[CH:1]1([O:6][C:7]([CH:8]([CH:9]2[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]2)[NH2:15])=[O:23])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

Reactant 3

HCID 6344Dichloromethane2×

HCID 6422Trifluoroacetic acid

HCID 67052641HCID 67052641, compound

Product 1

HCID 61279838Cyclopentyl 2-amino-2-cyclohexylacetate

Sources & evidence

ORD record: ord-e0f7ee7b9523450f8220e747578c2dcc
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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