Tetrahydrofuran → 1-(2-Bromo-4-fluoro-phenoxy)-2-methyl-propan-2-ol

Reaction equation

[Br:1][c:2]1[c:3]([O:4][CH2:5][C:6]([CH3:7])=[O:8])[cH:9][cH:10][c:11]([F:13])[cH:12]1.[CH2:17]1[O:18][CH2:19][CH2:20][CH2:21]1.[CH3:14][Mg:15][Cl:16]>>[Br:1][c:2]1[c:3]([O:4][CH2:5][C:6]([CH3:7])([OH:8])[CH3:14])[cH:9][cH:10][c:11]([F:13])[cH:12]1

Participants

Reactant 3

HCID 8028Tetrahydrofuran

HCID 22144837HCID 22144837, compound

HCID 178418332HCID 178418332, compound

Product 1

HCID 574450921-(2-Bromo-4-fluoro-phenoxy)-2-methyl-propan-2-ol

Sources & evidence

ORD record: ord-60864f5544524658ae6bc59269f5089e
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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