Hydrogen Bromide → 4-(5-Bromo-1,3,4-thiadiazol-2-yl)pyridine

HRID 831882Notes

Reaction equation

HRID 831882 reaction equation
[Br:13].[BrH:20].[N:14]([O-:15])=[O:16].[NH2:1][c:2]1[s:3][c:4](-[c:7]2[cH:8][cH:9][n:10][cH:11][cH:12]2)[n:5][n:6]1.[Na+:17].[Na+:19].[OH-:18].[OH2:21]>>[c:2]1([Br:20])[s:3][c:4](-[c:7]2[cH:8][cH:9][n:10][cH:11][cH:12]2)[n:5][n:6]1

Participants

7

Reactant 6

HCID 260Hydrogen Bromide2×HCID 923Sodium ion2×HCID 946NitriteHCID 961HydroxideHCID 962WaterHCID 1212692-Amino-5-(4-pyridyl)-1,3,4-thiadiazole

Product 1

HCID 576342624-(5-Bromo-1,3,4-thiadiazol-2-yl)pyridine

Sources & evidence

ORD record
ord-662fb5024d554ba18abe340250b1ef8d
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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