Hydrochloric Acid → 1-[2-(4-aminopiperidin-1-yl)ethyl]-7-methoxyquinolin-2(1H)-one

HRID 832676

Reaction equation

HRID 832676 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[cH:7][cH:8][c:9](=[O:29])[n:10]([CH2:13][CH2:14][N:15]3[CH2:16][CH2:17][CH:18]([NH:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:19][CH2:20]3)[c:11]2[cH:12]1.[ClH:30].[O:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[cH:7][cH:8][c:9](=[O:29])[n:10]([CH2:13][CH2:14][N:15]3[CH2:16][CH2:17][CH:18]([NH2:21])[CH2:19][CH2:20]3)[c:11]2[cH:12]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 59371209tert-butyl {1-[2-(7-methoxy-2-oxoquinolin-1(2H)-yl)ethyl]piperidin-4-yl}carbamate

Product 1

HCID 593982891-[2-(4-aminopiperidin-1-yl)ethyl]-7-methoxyquinolin-2(1H)-one

Sources & evidence

ORD record
ord-07c14de8d9134f079e38170565282288
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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