2,2,2-Trifluoroethanol → 1H-spiro[furo[3,4-c]pyridine-3,4'-piperidine]
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]2([O:12][CH2:13][c:14]3[c:15]2[cH:16][n:17][cH:18][cH:19]3)[CH2:20][CH2:21]1.[OH:22][CH2:23][C:24]([F:25])([F:26])[F:27]>>[NH:8]1[CH2:9][CH2:10][C:11]2([O:12][CH2:13][c:14]3[c:15]2[cH:16][n:17][cH:18][cH:19]3)[CH2:20][CH2:21]1Participants
3
Sources & evidence
- ORD record
- ord-274375edf10e43d48e8926e9289ea4aa
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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