Methanol → 2-(2,5-Dihydro-2-oxo-3-phenylfuran-4-yl)oxymethyl-4-isopropyl-6-methoxysaccharin

HRID 835006Notes

Reaction equation

HRID 835006 reaction equation
[C:1]([O-:2])(=[O:3])[O-:4].[CH3:38][OH:39].[CH3:40][N:41]([CH3:42])[CH:43]=[O:44].[Cl:19][CH2:20][N:21]1[S:22](=[O:23])(=[O:24])[c:25]2[cH:26][c:27]([O:36][CH3:37])[cH:28][c:29]([CH:33]([CH3:34])[CH3:35])[c:30]2[C:31]1=[O:32].[Cs+:5].[Cs+:6].[c:7]1([C:13]2=[CH:17][CH2:16][O:15][C:14]2=[O:18])[cH:8][cH:9][cH:10][cH:11][cH:12]1>>[O:2]([C:17]1=[C:13]([c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[C:14](=[O:18])[O:15][CH2:16]1)[CH2:20][N:21]1[S:22](=[O:23])(=[O:24])[c:25]2[cH:26][c:27]([O:36][CH3:37])[cH:28][c:29]([CH:33]([CH3:34])[CH3:35])[c:30]2[C:31]1=[O:32]

Participants

7

Reactant 6

HCID 887MethanolHCID 6228DimethylformamideHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 99951732-(Chloromethyl)-4-isopropyl-6-methoxybenzo[D]isothiazol-3(2H)-one 1,1-dioxideHCID 10986536HCID 10986536, compound

Product 1

HCID 106709072-(2,5-Dihydro-2-oxo-3-phenylfuran-4-yl)oxymethyl-4-isopropyl-6-methoxysaccharin

Sources & evidence

ORD record
ord-de1ddbb7768142ef9be6867d386cd632
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…