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Nickel → 2'-Amino-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-acetic acid ethyl ester

HRID 835355
Notes
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Reaction equation

HRID 835355 reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[cH:7][c:8](-[c:12]2[c:13]([N+:22]([O-:23])=[O:24])[cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[cH:9][cH:10][cH:11]1)=[O:25].[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[Ni:31]>>[CH2:1]([CH3:2])[O:3][C:4]([CH2:5][c:6]1[cH:7][c:8](-[c:12]2[c:13]([NH2:22])[cH:14][c:15]([C:18]([F:19])([F:20])[F:21])[cH:16][cH:17]2)[cH:9][cH:10][cH:11]1)=[O:25]
ParticipantsSources & evidenceReaction notes

Participants

4

Reactant 3

HCID 935NickelHCID 8028TetrahydrofuranHCID 672710532'-Nitro-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-acetic acid ethyl ester

Product 1

HCID 672715402'-Amino-4'-(trifluoromethyl)-[1,1'-biphenyl]-3-acetic acid ethyl ester

Sources & evidence

ORD record
ord-56c022335d074bef9aae6328c67f350f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes