Hydroxide → 5-isopropyl-1H-pyrrolo[2,3-b]pyridine

Reaction equation

[C:1](=[CH2:2])([CH3:3])[c:4]1[cH:5][c:6]2[c:7]([n:8][cH:9]1)[nH:10][cH:11][cH:12]2.[O:13]1[CH2:14][CH2:15][CH2:16][CH2:17]1.[OH-:18].[OH-:20].[Pd+2:19]>>[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][c:6]2[c:7]([n:8][cH:9]1)[nH:10][cH:11][cH:12]2

Participants

Reactant 4

HCID 961Hydroxide2×

HCID 8028Tetrahydrofuran

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 580868105-isopropenyl-1H-pyrrolo[2,3-b]pyridine

Product 1

HCID 599287205-isopropyl-1H-pyrrolo[2,3-b]pyridine

Sources & evidence

ORD record: ord-c236dc52f600430e84dabd2d25ad3b45
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…