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Sodium Ion → Tert-butyl 4-[1-[3-bromo-5-(trifluoromethyl)phenyl]ethoxymethyl]-4-phenylpiperidine-1-carboxylate

HRID 837108
Notes
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Reaction equation

HRID 837108 reaction equation
[Br:22][c:23]1[cH:24][c:25]([CH:33]([CH3:34])[Br:35])[cH:26][c:27]([C:29]([F:30])([F:31])[F:32])[cH:28]1.[CH3:38][N:39]([CH3:40])[CH:41]=[O:42].[H-:36].[Na+:37].[OH:1][CH2:2][C:3]1([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[CH2:4][CH2:5][N:6]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:7][CH2:8]1>>[O:1]([CH2:2][C:3]1([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[CH2:4][CH2:5][N:6]([C:9](=[O:10])[O:11][C:12]([CH3:13])([CH3:14])[CH3:15])[CH2:7][CH2:8]1)[CH:33]([c:25]1[cH:24][c:23]([Br:22])[cH:28][c:27]([C:29]([F:30])([F:31])[F:32])[cH:26]1)[CH3:34]
ParticipantsSources & evidenceReaction notes

Participants

6

Reactant 5

HCID 923Sodium IonHCID 6228DimethylformamideHCID 166653HydrideHCID 9994433Tert-butyl 4-(hydroxymethyl)-4-phenylpiperidine-1-carboxylateHCID 57980198HCID 57980198, compound

Product 1

HCID 58993627
Tert-butyl 4-[1-[3-bromo-5-(trifluoromethyl)phenyl]ethoxymethyl]-4-phenylpiperidine-1-carboxylate

Sources & evidence

ORD record
ord-39774fccfaa54261b7a69eb7f117f0e8
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes