N-methyl-2-pyrrolidone → 5-methyl-N-{3-methyl-4-[(6-methylpyridin-3-yl)oxy]phenyl}-5H-pyrrolo[3,2-d]pyrimidin-4-amine
Reaction equation
[CH3:12][c:13]1[cH:14][c:15]([NH2:16])[cH:17][cH:18][c:19]1[O:20][c:21]1[cH:22][n:23][c:24]([CH3:27])[cH:25][cH:26]1.[CH3:28][N:29]1[CH2:30][CH2:31][CH2:32][C:33]1=[O:34].[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][cH:9][n:10]2[CH3:11]>>[c:2]1([NH:16][c:15]2[cH:14][c:13]([CH3:12])[c:19]([O:20][c:21]3[cH:22][n:23][c:24]([CH3:27])[cH:25][cH:26]3)[cH:18][cH:17]2)[c:3]2[c:4]([n:5][cH:6][n:7]1)[cH:8][cH:9][n:10]2[CH3:11]Participants
4
Sources & evidence
- ORD record
- ord-16a2158646d4439b948ce0f54825da6e
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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