Water → 5-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine

Reaction equation

[Br:1][c:2]1[c:3]([F:21])[c:4]2[c:5]([n:6][cH:7]1)[n:8]([Si:11]([CH:12]([CH3:13])[CH3:14])([CH:15]([CH3:16])[CH3:17])[CH:18]([CH3:19])[CH3:20])[cH:9][cH:10]2.[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[OH2:22]>>[Br:1][c:2]1[c:3]([F:21])[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][cH:10]2

Participants

Reactant 3

HCID 962Water

HCID 8028Tetrahydrofuran

HCID 497589465-Bromo-4-fluoro-1-[tris(1-methylethyl)silyl]-1H-pyrrolo[2,3-b]pyridine

Product 1

HCID 534129385-bromo-4-fluoro-1H-pyrrolo[2,3-b]pyridine

Sources & evidence

ORD record: ord-35cbc0b436084a0cb1efabb7eafe711c
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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