Dichloromethane → 3-amino-N-cyclopropyl-2-hydroxy-3-methylbutanamide

HRID 838180

Reaction equation

[C:1]([O:2][C:3](=[O:4])[NH:7][C:8]([CH:9]([OH:10])[C:11]([NH:12][CH:13]1[CH2:14][CH2:15]1)=[O:16])([CH3:17])[CH3:18])([CH3:5])([CH3:6])[CH3:19].[Cl:20][CH2:21][Cl:22].[F:23][C:24]([F:25])([F:26])[C:27]([OH:28])=[O:29]>>[NH2:7][C:8]([CH:9]([OH:10])[C:11]([NH:12][CH:13]1[CH2:14][CH2:15]1)=[O:16])([CH3:17])[CH3:18]

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 67385732(2-Cyclopropylcarbamoyl-2-hydroxy-1,1-dimethylethyl)-carbamic acid tert-butyl ester

Product 1

HCID 575620933-amino-N-cyclopropyl-2-hydroxy-3-methylbutanamide

Sources & evidence

ORD record: ord-bee1269442c34ced888843a4f26b31a1
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Linked notes

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