2,4,5-Trichloroaniline → (Methylsulfonyl)(2,4,5-trichlorophenyl)amine
Reaction equation
[Cl:1][C:2]1[CH:8]=[C:7]([Cl:9])[C:6]([Cl:10])=[CH:5][C:3]=1[NH2:4].[CH3:11][S:12](Cl)(=[O:14])=[O:13]>C1(C)C(C)=CC=CC=1>[Cl:1][C:2]1[CH:8]=[C:7]([Cl:9])[C:6]([Cl:10])=[CH:5][C:3]=1[NH:4][S:12]([CH3:11])(=[O:14])=[O:13]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 2,4,5-trichloroaniline (39.3 g.), methane sulfonyl chloride (22.9 g.) and 100 ml. of xylene were heated together under reflux conditions for 18 hours. The mixture was then allowed to cool, which formed a brown precipitate. The product was worked up in the same manner as set forth in Example 1 to yield 24.0 g. of product, m.p. 144°-145° C.
Workup
- temperatureto cool
- customwhich formed a brown precipitate
- customto yield 24.0 g
Sources & evidence
- ORD record
- ord-821e4309e95646ffa6a425d6d741ea1e
- Source dataset
- uspto-grants-1978_06
- Patent number
- US04093445
Reaction notes
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