2-Formylfuran-5-sulfonate → N-n-Butyl-alpha-(2-sulfofuran-5yl)nitrone

HRID 842977Notes

Reaction equation

HRID 842977 reaction equation
[CH:1]([C:3]1[O:7][C:6]([S:8]([OH:11])(=[O:10])=[O:9])=[CH:5][CH:4]=1)=O.[Na].[CH2:13]([NH:17][OH:18])[CH2:14][CH2:15][CH3:16]>>[CH2:13]([N+:17]([O-:18])=[CH:1][C:3]1[O:7][C:6]([S:8]([OH:11])(=[O:10])=[O:9])=[CH:5][CH:4]=1)[CH2:14][CH2:15][CH3:16]

Participants

4

Reactant 3

HCID 27240012-Formylfuran-5-sulfonateHCID 5360545Sodium2×HCID 10034579N-Hydroxy-1-butanamine

Product 1

HCID 86754424N-n-Butyl-alpha-(2-sulfofuran-5yl)nitroneYield 6.7%

Procedure

Following the procedure of Example 1 above and using 5-formylfuran-2-sulfonic acid, sodium salt hydrate and N-n-butylhydroxylamine, the title compound was prepared in 6.7% yield as the sodium salt, m.p. 212.8° C. (dec).

Sources & evidence

ORD record
ord-5a2b0920d6054d3d9e10a73c19358b53
Source dataset
uspto-grants-2002_04
Patent number
US06376540B1

Reaction notes

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