3-Phenylprop-2-Enal → 5-(4-Phenyl-1,3-butadienyl)-1,2-dithiol-3-thione

Reaction equation

[CH:1](=O)[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH3:11][C:12]1[S:16][S:15][C:14](=[S:17])[CH:13]=1>>[C:4]1([CH:3]=[CH:2][CH:1]=[CH:11][C:12]2[S:16][S:15][C:14](=[S:17])[CH:13]=2)[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1

Participants

Reactant 2

HCID 3073-Phenylprop-2-Enal

HCID 1378993H-1,2-Dithiole-3-thione, 5-methyl-

Product 1

HCID 539425735-(4-Phenyl-1,3-butadienyl)-1,2-dithiol-3-thione

Procedure

In the same manner as in Example 1, a corresponding cinnamaldehyde derivative (i.e., 4-chloro-cinnamaldehyde, 4-methoxy-cinnamaldehyde, 4-dimethylamino-cinnamaldehyde, p-methyl-cinnamaldehyde, o-chloro-cinnamaldehyde or m-methyl-cinnamaldehyde) was reacted with 5-methyl-1,2-dithiol-3-thione to prepare the following compounds.

Workup

customto prepare the following compounds

Sources & evidence

ORD record: ord-8da12743090d4d08b19c9191b2d334a4
Source dataset: uspto-grants-1988_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04760078

Reaction notes

Loading…