Reaction equation
[F:1][C:2]1[C:11]2[O:10][CH2:9][C:8]3[CH:12]=[C:13]([C:15]([OH:17])=O)[S:14][C:7]=3[C:6]=2[CH:5]=[C:4]([F:18])[CH:3]=1.[Cl:19][C:20]1[CH:27]=[CH:26][CH:25]=[CH:24][C:21]=1[NH:22][CH3:23]>>[Cl:19][C:20]1[CH:27]=[CH:26][CH:25]=[CH:24][C:21]=1[N:22]([CH3:23])[C:15]([C:13]1[S:14][C:7]2[C:6]3[CH:5]=[C:4]([F:18])[CH:3]=[C:2]([F:1])[C:11]=3[O:10][CH2:9][C:8]=2[CH:12]=1)=[O:17]Participants
3
Procedure
Following the procedure of Example 70 and General Procedure B, 142bp was prepared from 6,8-difluoro-4H-thieno[3,2-c]chromene-2-carboxylic acid and 2-chloro-N-methylaniline. MS: (ESI+)=392.1
Sources & evidence
- ORD record
- ord-49cb9c3174f74135a3e8ce849ddb0c72
- Source dataset
- uspto-grants-2014_09
- Patent number
- US08846762B2
Linked notes
Loading…