2-Aminothiophenol → HCID 20566346, compound
Reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[SH:8].[Na].Cl[CH2:11][C:12]1[N:16]=[C:15]([CH2:17]Cl)[O:14][N:13]=1>C(O)C>[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[S:8][CH2:11][C:12]1[N:16]=[C:15]([CH2:17][S:8][C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[NH2:1])[O:14][N:13]=1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
2-Aminobenzenethiol (5.0 g, 0.04 mol) was dissolved in a solution of sodium (0.92 g, 0.04 mol) in ethanol (50 ml) and 3,5-di(chloromethyl)-1,2,4-oxadiazole (3.3 g, 0.02 mol) was added. After filtration of the mixture, the filtrate was collected and the solvent removed to yield the crude product which on re-crystallisation from isopropanol gave 3,5,-di-(2-aminophenylthiomethyl)-1,2,4-oxadiazole, m.p. 68°.