Hydrochloric Acid → HCID 178479039, compound

HRID 849081

Reaction equation

HRID 849081 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:3]=1.[ClH:15]>[Pt]=O>[ClH:15].[CH:9]1([CH2:8][CH:4]2[NH:3][C:2](=[NH:1])[CH2:7][CH2:6][CH2:5]2)[CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 939026-Benzylpyridin-2-amine

Product 1

HCID 178479039HCID 178479039, compound

Reagents, catalysts & solvents 1

HCID 82844Platinum oxide (PtO)Catalyst

Procedure

The 2-amino-6-benzylpyridine was reduced as in Example 94, except platinum oxide was used as the catalyst. The product was obtained as an oil which was dissolved in 1 N HCl and lyophilized to give a white solid. The solid was recrystallized from EtOAc to give the desired title compound as white crystals. The analysis of the product was found to be consistent with the proposed structure.

Workup

  1. customThe product was obtained as an oil which
  2. customto give a white solid
  3. customThe solid was recrystallized from EtOAc

Sources & evidence

ORD record
ord-ab961bebbe72482badb3276f57ec740a
Source dataset
uspto-grants-2000_01
Patent number
US06011028

Linked notes

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