HCID 178418361, compound → HCID 178478657, compound
Reaction equation
[ClH:1].[N+:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[CH2:11][CH:12]1[NH:18][C:17](=[NH:19])[CH2:16][CH2:15][CH2:14][CH2:13]1)([O-])=O.[H][H]>C(O)C.[Rh]>[ClH:1].[ClH:1].[NH:19]=[C:17]1[NH:18][CH:12]([CH2:11][CH:6]2[CH2:7][CH2:8][CH2:9][CH2:10][CH:5]2[NH2:2])[CH2:13][CH2:14][CH2:15][CH2:16]1Participants
5
Reactant 2
Product 1
Reagents, catalysts & solvents 2
Conditions
- Temperature
- 60 °C
Procedure
The product of Example 270 (0.262 g, 0.9 mmol) was dissolved in ethanol, treated with 5% Rhodium on Carbon under 60 psi of Hydrogen and warmed to 60° C. to give the title product (66 mg, 0.22 mmol).
Sources & evidence
- ORD record
- ord-a520f14e055e4aaf94b7fdec71f943b4
- Source dataset
- uspto-grants-2000_01
- Patent number
- US06011028
Reaction notes
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