Trifluoroacetic acid → HCID 69039797, compound
Reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][CH:17]=1)[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][OH:14])=[CH:9][CH:8]=1.[N-:18]=[C:19]=[O:20].[K+].FC(F)(F)C(O)=O>C1C=CC=CC=1>[F:1][C:2]1[CH:3]=[C:4]([CH:15]=[CH:16][CH:17]=1)[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][O:14][C:19](=[O:20])[NH2:18])=[CH:9][CH:8]=1Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
In analogy to the procedure described in Example 24 b), the reaction of [4-(3-fluoro-benzyloxy)-phenyl]-methanol with potassium isocyanate and trifluoroacetic acid in benzene yielded the carbamic acid 4-(3-fluoro-benzyloxy)-benzyl ester as a white solid; MS: m/e=293 (M+NH4)+.
Sources & evidence
- ORD record
- ord-65ecf41e23cb414b856d00a353fc0b2e
- Source dataset
- uspto-grants-2007_08
- Patent number
- US07253318B2
Reaction notes
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