Ethyl Acetate → 705-04-4
Reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9](=[O:11])[CH3:10])=[N:6][CH:7]=1.CC[O:14]C(C)=O>>[CH3:10][C:9]([N:8]=[C:5]1[N:6]([OH:14])[CH:7]=[C:2]([Br:1])[CH:3]=[CH:4]1)=[O:11]Participants
3
Procedure
Prepared according to the procedure described in EXAMPLE 9, Step 4, but using N-(5-bromo-pyridin-2-yl)-acetamide from Step 1 as starting material. Flash chromatography (EtOAc) afforded the title compound as a white solid.
Workup
- customPrepared
Sources & evidence
- ORD record
- ord-78cb80c9938a4559885a74968dab8422
- Source dataset
- uspto-grants-2006_12
- Patent number
- US07153968B2
Reaction notes
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